Clinical Implications of Defective B-Type Natriuretic Peptide
نویسندگان
چکیده
منابع مشابه
Perioperative B-type Natriuretic Peptide/N-terminal pro-B-type Natriuretic PeptideNext Steps to Clinical Practice
Anesthesiology, V 123 • No 2 246 August 2015 T HE heart is not only a pumping organ but also an endocrine organ. B-type natriuretic peptide (BNP) is secreted primarily by cardiac ventricular myocytes in response to increased ventricular wall stress induced by volume expansion, pressure overload, or ischemia.1 BNP protein formation begins with intracellular translation into a large preprohormone...
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with increased concentrations of GAPDH mRNA. Because circulating GAPDH mRNA in cancer patients was thought to originate in apoptotic cancer cells (2, 5), the increased concentrations of GAPDH mRNA detected may be caused by apoptosis in the placental residue in our case. We conclude that real-time quantitative RT-PCR is a sensitive method to monitor changing mRNA concentrations resulting from ap...
متن کاملClinical and Biochemical Assessments of Circulating B-Type Natriuretic Peptide as a Useful Marker in Pediatric Cardiac Patients
Background Although the left ventricle is the major site of BNP secretion in response to cardiac pressure or volume overload, the myocytes of both atria and ventricles secrete B- type natriuretic peptide (BNP). This study aimed to assess and compare the plasma levels of BNP in common pediatric cardiac diseases to clarify its pathophysiological role and evaluate its po...
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The structure of the mouse natriuretic peptide type-B (BNP) gene was determined by isolating and sequencing genomic clones. The mouse BNP gene was structurally similar to other natriuretic peptide genes and comprised three exons and two introns. Expression of the mouse BNP gene was found only in cardiac tissue as determined by ribonuclease protection analyses. Initiation of transcription was 31...
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renal failure: standards and audit measures (third edition). London: UK Renal Association, 2002. 2. Walker KS, Seth J. Stability of parathyroid hormone in blood from renal patients on haemodialysis. Ann Clin Biochem 2000;37:800–1. 3. Omar H, Chamberlin A, Walker V, Wood PJ. Immulite 2000 parathyroid hormone assay: stability of parathyroid hormone in EDTA blood kept at room temperature for 48 ho...
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ژورنال
عنوان ژورنال: Clinical Cardiology
سال: 2009
ISSN: 0160-9289
DOI: 10.1002/clc.20480